Pityriasis alba
Definition
This is a pattern of dermatitis in
which hypopigmentation is the most conspicuous feature. Some erythema and
scaling usually precede the development of hypopigmentation but these are often
relatively mild.
Epidemiology
Age
Pityriasis
alba occurs predominantly in children between the ages of 3 and 16 years.
Sex
The
sexes are equally susceptible.
Associated
diseases
Pityriasis
alba is often a manifestation of atopic eczema but it is not confined to atopic
individuals.
Clinical
features
The lesions consist
of round, oval or irregular hypo
pigmented ill-defined macules and patches.
They are often slightly erythematous and have fine scaling. Initially, the
erythema may be conspicuous and there may even be minimal serous crusting.
Later, the erythema subsides completely and, at the stage at which the lesions
are commonly seen by a physician, they show only persistent fine dry, powdery
scaling and hypopigmentation. It is
this that usually induces the patient to seek advice. The hypopigmentation is
most conspicuous in pigmented skin, and in lighter skins it
becomes more apparent during the summer months when the surrounding skin is
tanned. This dermatosis is generally asymptomatic, but some patients complain
of itching and burning
There are usually several patches
ranging from 0.5 to 2 cm in diameter, but they may be larger, especially on the
trunk. In children the lesions are often confined to the face, and are most
common on the cheeks and around the mouth and chin. In 20% of affected children
the neck, arms and shoulders are involved as well as the face. Less commonly
the face is spared and there are scattered lesions on the trunk and limbs.
Although the patches of hypomelanosis often remain stationary and
unchanged for several years, they usually (but not always) clear spontaneously
after puberty.
Differential
diagnosis
The age incidence, fine scaling and distribution of the
lesions usually suggest the diagnosis. Naevus depigmentosus most commonly
presents at birth or before 3 years of age and most often causes single, well‐marginated lesions on the trunk.
However, this condition may be difficult to distinguish from pityriasis alba
when it occurs on the face and in cases of later onset. Nummular dermatitis in
an atopic child is intensely pruritic, and the lesions are larger and more edematous.
In older children and adults, early trunk lesions may be mistaken for psoriasis
but the distribution and the relatively mild scaling should exclude this
diagnosis.
Disease
course and prognosis
Recurrent
crops of new lesions may develop at intervals. The average duration of the common
facial form in childhood is a year or more.
Treatment
Response to treatment is often
disappointing, mainly because the hypopigmentation takes a long time to
recover. The scaling may be reduced by a bland emollient cream. Mild topical corticosteroid such as
hydrocortisone is helpful if inflammation
persists. Topical tacrolimus and pimecrolimus are effective in facial atopic
eczema and seem likely to prove helpful in pityriasis alba.
Therapeutic ladder
First
line
·
Emollient
Second
line
·
Mild topical corticosteroids
Third
line
·
Topical tacrolimus or pimecrolimus